Package | Dosage | Price | Price per Dose | |
---|---|---|---|---|
Dosage: 150mg | ||||
56 pill | 150mg | AUD1,794.96 | AUD32.05 | |
28 pill | 150mg | AUD1,076.97 | AUD38.46 | |
Dosage: 200mg | ||||
56 pill | 200mg | AUD2,034.29 | AUD36.33 | |
28 pill | 200mg | AUD1,196.63 | AUD42.74 |
Nilotinib Description
Overview
Nilotinib is a targeted cancer medicine used to treat certain blood cancers. It belongs to the class of BCR-ABL tyrosine kinase inhibitors. By blocking the abnormal enzyme produced by the Philadelphia chromosome, nilotinib can slow or stop the growth of malignant cells. This review explains how it works, how to take it, and what to expect when you order it from an online pharmacy with a valid prescription.
How it works
Nilotinib binds to the BCR-ABL protein and several related kinases. In chronic myeloid leukemia and related leukemias, this enzyme sends signals that drive uncontrolled cell growth. Inhibiting the enzyme reduces cell division and can promote cancer cell death. The drug can also affect normal cells, so monitoring is important to balance benefit and risk.
How to take Nilotinib
Take the medication exactly as prescribed by your clinician. The typical regimen for chronic myeloid leukemia is a twice-daily dose taken on an empty stomach. Do not eat for at least two hours before a dose and do not take a dose with a meal. Swallow tablets whole with water; do not crush or chew them. If you miss a dose, contact your pharmacist or doctor for advice on the next step.
Drug interactions
Nilotinib interacts with medicines that affect liver enzymes, especially CYP3A4. Antifungal drugs, certain antibiotics, some anticonvulsants, and cholesterol medicines can raise or lower nilotinib levels. It may also interact with antacids, supplements, and grapefruit juice. Always tell your healthcare team about all medicines, vitamins, and herbal products you use.
Common and serious side effects
Common effects include tiredness, nausea, stomach pain, diarrhea or constipation, rash, and itching. Headache, dizziness, and muscle cramps are also reported. Some patients develop high blood sugar, changes in lipid levels, or weight changes. More serious risks include QT interval prolongation on the heart monitor, pancreatitis, liver enzyme elevations, and low blood counts. Seek urgent care for chest pain, fainting, severe shortness of breath, yellowing of the skin, or unusual bleeding.
Warnings and precautions
Nilotinib requires regular medical follow-up. People with heart disease, electrolyte abnormalities, liver or kidney problems, or a history of arrhythmias need careful assessment. The drug can affect heart rhythm and lipid levels, so monitoring is essential. It should be avoided in pregnancy unless advised by a clinician. Inform all providers about your treatment plan.
Storage and handling
Store at room temperature away from moisture and heat. Keep the bottle tightly closed and out of reach of children. Do not use after the expiry date. If you miss a dose, contact your pharmacist for guidance on the best next step. Do not dispose of medicines in household wastewater unless instructed.